metolazone decreases results of liraglutide by pharmacodynamic antagonism. Use Warning/Watch. Thiazide diuretics can lower insulin sensitivity thereby bringing about glucose intolerance and hyperglycemia.
estrogens conjugated artificial decreases outcomes of liraglutide by pharmacodynamic antagonism. Use Warning/Check. Estrogens could reduce hypoglycemic outcomes of antidiabetics by impairing glucose tolerance. Watch for glycemic Regulate in diabetic sufferers.
GLP-1 is really a physiological regulator of urge for food and calorie ingestion, as well as GLP-one receptor is present in quite a few areas of the brain involved in appetite regulation. In animal scientific tests, peripheral administration of liraglutide resulted while in the presence of liraglutide in unique Mind locations regulating urge for food, such as the hypothalamus.
The pen is designed to make the injections uncomplicated for you to administer to oneself after a day, this means you’ll have finish control above when and where you go ahead and take medication.
Liraglutide can decelerate the speed at which your stomach empties, which could have an effect on how perfectly oral medicines are absorbed.
Should you (or your teenager) overlook your every day dose of Saxenda®, just take the following each day dose as regular on the following day. Do not acquire an extra dose of Saxenda® or improve the dose on the subsequent day to create up to the missed dose.
levonorgestrel oral decreases results of liraglutide by pharmacodynamic antagonism. Use Caution/Watch. Oral contraceptives may well reduce hypoglycemic outcomes of antidiabetics by impairing more info glucose tolerance. Watch for glycemic Manage in diabetic patients.
bazedoxifene/conjugated estrogens decreases consequences of liraglutide by pharmacodynamic antagonism. Use Caution/Observe. Estrogens may well lower hypoglycemic effects of antidiabetics by impairing glucose tolerance. Keep an eye on for glycemic Regulate in diabetic clients.
Use Caution/Monitor. Antidiabetic brokers tend to be utilised in combination; dosage adjustments could possibly be demanded when initiating or discontinuing antidiabetic agents.
There aren't any info within the presence of liraglutide in human breast milk; liraglutide was current while in the milk of lactating rats
If You can not tolerate the recommended upkeep dosage (3 mg when everyday), your medical professional will probable prevent your Saxenda therapy. Speak with your doctor When you have questions about your dosage of Saxenda.
It's not necessarily acknowledged if SAXENDA is safe and successful when taken with other prescription more than-the-counter medicines or herbal weight loss products and solutions.
Speak to your individuals about possible Uncomfortable side effects, together with nausea, and the way to manage them If sufferers cannot tolerate an increased dose throughout dose escalation, look at delaying escalation for approximately one 7 days. If a individual can not tolerate the 3 mg dose, discontinue treatment1
The most typical side effects incorporate nausea, vomiting, diarrhea, constipation, and skin reactions in the injection web-site. Luckily, these Uncomfortable side effects commonly recuperate by themselves after a while. But should you find the side effects much too awkward, you'll be able to usually fall back all the way down to the decrease dose and take a look at the higher dose all over again later.